The ability to reach F#, low E and beyond puts serious demands on most traditional equipment. The fundamental of the low E hovers at what is considered the threshold of human hearing.
Fortunately a bass note is comprised of significantly more sound information than just its fundamental frequency - multiple octaves and intervals actually. And most interesting is that the fundamental is only one half (or less) as loud as the octave that lives above it in its normal tonal structure.
This helps explain how musical instrument speaker cabinets have been able to reasonably do their jobs despite not being truly up to the task. There are very few speaker cabinets that can reproduce 40Hz yet we seem to be able to live with the amplified results. This is because most cabinets are capable of reproducing the octave above the fundamental quite well.
That we perceive hearing 40Hz and below through speakers that are incapable of it can be attributed to Psychoacoustics, in much the same way that we infer low frequencies over telephones.
So how does one reproduce these very low frequencies? The best way is to not rely on speakers - go direct. The limitations are then foisted onto recording consoles, house PA systems, or home/car playback equipment.
For the sake of self-monitoring, rehearsing and performance the best way is to be certain your gear is capable of handling the octave above your lowest note. This seems like a simple solution but it's harder than it sounds. The vast majority of musical instrument speaker cabinets have a difficult time supporting the octave above low B, despite what manufacturer's specifications may indicate.
If manufacturer's specs aren't to be trusted, then what? Well, if you like the sound that's coming out of your rig then don't sweat it. Just be careful at high volumes as you are flirting with the limitations of the drivers and asking a great deal of your speakers.
If you want to know specifically what your rig is capable of then take your cabinet(s) to a shop that specializes in sound reinforcement repair to have diagnostics run. They can tell you what your speakers are giving you and you can decide for yourself what comes next.